USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: P68036 USC-OGP 2-DE database:  P68036 P68036 General information about the entry View entry in simple text format Entry name UB2L3_HUMAN Primary accession number P68036 Secondary accession number(s) P51966 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Ubiquitin-conjugating enzyme E2 L3; EC=2.3.2.23 {ECO:0000269|PubMed:20061386}; AltName: Full=E2 ubiquitin-conjugating enzyme L3; AltName: Full=L-UBC; AltName: Full=UbcH7; AltName: Full=Ubiquitin carrier protein L3; AltName: Full=Ubiquitin-conjugating enzyme E2-F1; AltName: Full=Ubiquitin-protein ligase L3;. Gene name Name=UBE2L3 Synonyms=UBCE7, UBCH7 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_6-11 {PLATELET 6-11} Homo sapiens (Human)   map experimental info   PLATELET_6-11 MAP LOCATIONS: SPOT OGP-1080: pI=8.23; Mw=16543 Cross-references UniProtKB/Swiss-Prot P68036; UB2L3_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name UB2L3_HUMAN Primary accession number P68036 Secondary accession number(s) B2R4A7 B4DDG1 B4DSZ4 E7EWS7 P51966 P70653 Q9HAV1 Sequence was last modified on  October 11, 2004 (version 1) Annotations were last modified on  March 15, 2017 (version 139) Name and origin of the protein Description RecName: Full=Ubiquitin-conjugating enzyme E2 L3; EC=2.3.2.23 {ECO:0000269|PubMed:20061386}; AltName: Full=E2 ubiquitin-conjugating enzyme L3; AltName: Full=L-UBC; AltName: Full=UbcH7; AltName: Full=Ubiquitin carrier protein L3; AltName: Full=Ubiquitin-conjugating enzyme E2-F1; AltName: Full=Ubiquitin-protein ligase L3; Gene name Name=UBE2L3 Synonyms=UBCE7, UBCH7 Encoded on Name=UBE2L3; Synonyms=UBCE7, UBCH7 Keywords 3D-structure; Acetylation; Alternative splicing; ATP-binding; Complete proteome; Cytoplasm; Direct protein sequencing; Nucleotide-binding; Nucleus; Reference proteome; Transcription; Transcription regulation; Transferase; Ubl conjugation; Ubl conjugation pathway. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL S81003; AAB36017.1; -; mRNA EMBL X92962; CAA63538.1; -; mRNA EMBL AJ000519; CAA04156.1; -; mRNA EMBL AF300336; AAG17922.1; -; Genomic_DNA EMBL CR456606; CAG30492.1; -; mRNA EMBL AK293179; BAG56722.1; -; mRNA EMBL AK299985; BAG61806.1; -; mRNA EMBL AK311761; BAG34704.1; -; mRNA EMBL AP000553; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AP000557; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AP000558; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471095; EAW59459.1; -; Genomic_DNA EMBL BC053368; AAH53368.1; -; mRNA CCDS CCDS13790.1; -. [P68036-1]; . CCDS CCDS58795.1; -. [P68036-3]; . CCDS CCDS58796.1; -. [P68036-2]; . RefSeq NP_001243284.1; NM_001256355.1. [P68036-3]; . RefSeq NP_001243285.1; NM_001256356.1. [P68036-2]; . RefSeq NP_003338.1; NM_003347.3. [P68036-1]; . UniGene Hs.108104; -; . PDB 1C4Z; X-ray; 2.60 A; D=1-154 PDB 1FBV; X-ray; 2.90 A; C=1-154 PDB 3SQV; X-ray; 3.30 A; C/D=1-154 PDB 3SY2; X-ray; 3.27 A; C/D=1-154 PDB 4Q5E; X-ray; 1.87 A; C=1-154 PDB 4Q5H; X-ray; 2.00 A; C=1-154 PDB 5HPT; X-ray; 2.84 A; C/F=2-154 PDBsum 1C4Z; -; . PDBsum 1FBV; -; . PDBsum 3SQV; -; . PDBsum 3SY2; -; . PDBsum 4Q5E; -; . PDBsum 4Q5H; -; . PDBsum 5HPT; -; . ProteinModelPortal P68036; -; . SMR P68036; -; . BioGrid 113180; 136; . DIP DIP-6124N; -; . IntAct P68036; 29; . MINT MINT-5002693; -; . STRING 9606.ENSP00000344259; -; . iPTMnet P68036; -; . PhosphoSitePlus P68036; -; . SwissPalm P68036; -; . BioMuta UBE2L3; -; . DMDM 54039805; -; . OGP P51966; -; . UCD-2DPAGE P68036; -; . EPD P68036; -; . MaxQB P68036; -; . PaxDb P68036; -; . PeptideAtlas P68036; -; . PRIDE P68036; -; . TopDownProteomics P68036-1; -. [P68036-1]; . TopDownProteomics P68036-2; -. [P68036-2]; . DNASU 7332; -; . Ensembl ENST00000342192; ENSP00000344259; ENSG00000185651. [P68036-1]; . Ensembl ENST00000458578; ENSP00000400906; ENSG00000185651. [P68036-3]; . Ensembl ENST00000545681; ENSP00000445931; ENSG00000185651. [P68036-2]; . GeneID 7332; -; . KEGG hsa:7332; -; . UCSC uc002zva.2; human. [P68036-1]; . CTD 7332; -; . DisGeNET 7332; -; . GeneCards UBE2L3; -; . HGNC HGNC:12488; UBE2L3; . HPA HPA045609; -; . HPA HPA062415; -; . MIM 603721; gene; . neXtProt NX_P68036; -; . OpenTargets ENSG00000185651; -; . Orphanet 536; Systemic lupus erythematosus; . PharmGKB PA37137; -; . eggNOG KOG0422; Eukaryota; . eggNOG COG5078; LUCA; . GeneTree ENSGT00760000119012; -; . HOGENOM HOG000233455; -; . HOVERGEN HBG063308; -; . InParanoid P68036; -; . KO K04552; -; . OMA ADGQIAC; -; . OrthoDB EOG091G0QDO; -; . PhylomeDB P68036; -; . TreeFam TF313043; -; . BRENDA 2.3.2.B6; 2681; . Reactome R-HSA-8866652; Synthesis of active ubiquitin: roles of E1 and E2 enzymes; . Reactome R-HSA-8866654; E3 ubiquitin ligases ubiquitinate target proteins; . Reactome R-HSA-983168; Antigen processing: Ubiquitination & Proteasome degradation; . SignaLink P68036; -; . UniPathway UPA00143; -; . ChiTaRS UBE2L3; human; . EvolutionaryTrace P68036; -; . GeneWiki UBE2L3; -; . GenomeRNAi 7332; -; . PRO PR:P68036; -; . Proteomes UP000005640; Chromosome 22; . Bgee ENSG00000185651; -; . CleanEx HS_UBE2L3; -; . ExpressionAtlas P68036; baseline and differential; . Genevisible P68036; HS; . GO GO:0005737; C:cytoplasm; IDA:UniProtKB; . GO GO:0005829; C:cytosol; IDA:HPA; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005654; C:nucleoplasm; TAS:Reactome; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0000151; C:ubiquitin ligase complex; TAS:UniProtKB; . GO GO:0005524; F:ATP binding; IEA:UniProtKB-KW; . GO GO:0019899; F:enzyme binding; TAS:UniProtKB; . GO GO:0003723; F:RNA binding; IDA:UniProtKB; . GO GO:0003713; F:transcription coactivator activity; IDA:UniProtKB; . GO GO:0061631; F:ubiquitin conjugating enzyme activity; IDA:MGI; . GO GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB; . GO GO:0097027; F:ubiquitin-protein transferase activator activity; IGI:ParkinsonsUK-UCL; . GO GO:0004842; F:ubiquitin-protein transferase activity; IDA:UniProtKB; . GO GO:0044770; P:cell cycle phase transition; IMP:UniProtKB; . GO GO:0008283; P:cell proliferation; IMP:UniProtKB; . GO GO:0006464; P:cellular protein modification process; TAS:UniProtKB; . GO GO:0071385; P:cellular response to glucocorticoid stimulus; IDA:UniProtKB; . GO GO:0071383; P:cellular response to steroid hormone stimulus; IMP:UniProtKB; . GO GO:1903955; P:positive regulation of protein targeting to mitochondrion; IMP:ParkinsonsUK-UCL; . GO GO:0031398; P:positive regulation of protein ubiquitination; IGI:ParkinsonsUK-UCL; . GO GO:0051443; P:positive regulation of ubiquitin-protein transferase activity; IGI:ParkinsonsUK-UCL; . GO GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB; . GO GO:0000209; P:protein polyubiquitination; IDA:UniProtKB; . GO GO:0016567; P:protein ubiquitination; IDA:UniProtKB; . GO GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IEA:Ensembl; . GO GO:0006355; P:regulation of transcription; DNA-templated; IDA:UniProtKB GO GO:0006351; P:transcription; DNA-templated; IEA:UniProtKB-KW GO GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:UniProtKB; . Gene3D 3.10.110.10; -; 1; . InterPro IPR000608; UBQ-conjugat_E2; . InterPro IPR023313; UBQ-conjugating_AS; . InterPro IPR016135; UBQ-conjugating_enzyme/RWD; . Pfam PF00179; UQ_con; 1; . SUPFAM SSF54495; SSF54495; 1; . PROSITE PS00183; UBIQUITIN_CONJUGAT_1; 1; . PROSITE PS50127; UBIQUITIN_CONJUGAT_2; 1; .

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